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The initiation of de novo methylation of foreign DNA integrated into a mammalian genome is not exclusively targeted by nucleotide sequence.

The de novo methylation of foreign DNA integrated into the mammalian genome is a fundamental process whose mechanism has not yet been elucidated. We have studied de novo methylation in adenovirus type 12 (Ad12) genomes inserted into the genomes of Ad12-induced hamster tumor cells. De novo methylatio...

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Autores principales: Orend, G, Knoblauch, M, Kämmer, C, Tjia, S T, Schmitz, B, Linkwitz, A, Meyer, G, Maas, J, Doerfler, W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC188696/
https://ncbi.nlm.nih.gov/pubmed/7815498
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