Microinjection of synthetic amyloid beta-protein in monkey cerebral cortex fails to produce acute neurotoxicity.

The cerebral deposition of amyloid beta protein (A beta P) is an early pathogenetic event in Alzheimer's disease (AD). Recent studies suggest both neurotoxic and neurotrophic effects of A beta P in vitro. Because progressive A beta P deposition and surrounding neuritic dystrophy occur spontaneo...

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Autores principales: Podlisny, M. B., Stephenson, D. T., Frosch, M. P., Tolan, D. R., Lieberburg, I., Clemens, J. A., Selkoe, D. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886844/
https://ncbi.nlm.nih.gov/pubmed/8424453
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