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Dexamethasone prevents autoimmune nephritis and reduces renal expression of Ia but not costimulatory signals.

Although glucocorticoids are a conventional treatment for lupus nephritis, the cellular and molecular mechanisms responsible for preventing renal injury are unknown. MRL-lpr mice develop an aggressive autoimmune nephritis. As these mice become nephritic, there is an increase in the renal expression...

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Detalhes bibliográficos
Main Authors: Jevnikar, A. M., Singer, G. G., Brennan, D. C., Xu, H. W., Kelley, V. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886682/
https://ncbi.nlm.nih.gov/pubmed/1355633
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