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Effect of serum amyloid P component level on transthyretin-derived amyloid deposition in a transgenic mouse model of familial amyloidotic polyneuropathy.

To elucidate the pathogenesis of amyloid deposition associated with familial amyloidotic polyneuropathy (FAP), we developed several transgenic mouse lines carrying the human mutant transthyretin (TTR) gene. We found that human TTR and mouse serum amyloid P component (SAP) are deposited as amyloid in...

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Detalhes bibliográficos
Main Authors: Murakami, T., Yi, S., Maeda, S., Tashiro, F., Yamamura, K., Takahashi, K., Shimada, K., Araki, S.
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886609/
https://ncbi.nlm.nih.gov/pubmed/1497094
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