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The NIH-3 immunodeficient mouse is a model for Lyme borreliosis myositis and carditis.

Experimental infection of immunodeficient NIH-3 (N:NIH-bg-nu-xid) mice with Borrelia burgdorferi was found to result in multisystem histopathologic lesions. In addition to T-cell deficiency due to the nude mutation, these mice have an x-linked defect affecting the B-cell maturation and the beige mut...

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Autori principali: Defosse, D. L., Duray, P. H., Johnson, R. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886584/
https://ncbi.nlm.nih.gov/pubmed/1632468
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