Cationic immune complex arthritis in mice--a new model. Synergistic effect of complement and interleukin-1.

A novel cationic immune-complex-mediated arthritis (ICA) model was developed in mice. The highly cationic protein lysozyme was coupled to poly-L-lysine (PLL) and injected intra-articularly into the knee joint of the mouse, shortly after systemic administration of specific antibodies. A vehement join...

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Dettagli Bibliografici
Autori principali: van Lent, P. L., van den Bersselaar, L. A., van den Hoek, A. E., van de Loo, A. A., van den Berg, W. B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886551/
https://ncbi.nlm.nih.gov/pubmed/1605310
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