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Deletions in one domain of the Friend virus-encoded membrane glycoprotein overcome host range restrictions for erythroleukemia.

Although the Friend virus-encoded membrane glycoprotein (gp55) activates erythropoietin receptors (EpoR) to cause erythroblastosis only in certain inbred strains of mice but not in other species, mutant viruses can overcome aspects of mouse resistance. Thus, mice homozygous for the resistance allele...

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Bibliographische Detailangaben
Hauptverfasser: Hoatlin, M E, Ferro, F E, Geib, R W, Fox, M T, Kozak, S L, Kabat, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC188652/
https://ncbi.nlm.nih.gov/pubmed/7815553
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