Application of a multiprobe RNase protection assay and junctional sequences to define V beta gene diversity in Sezary syndrome.

Nineteen patients with mycosis fungoides/Sezary syndrome (MF/SZ), a malignancy of the mature helper T-cell phenotype (CD4+TCR alpha beta+), were screened for clonotypic V beta expansions in peripheral blood with a multiprobe RNase protection assay. A different predominant V beta gene was identified...

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Bibliographic Details
Main Authors: Kono, D. H., Baccala, R., Balderas, R. S., Kovac, S. J., Heald, P. W., Edelson, R. L., Theofilopoulos, A. N.
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886373/
https://ncbi.nlm.nih.gov/pubmed/1562047
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