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Oligomeric rearrangement of tick-borne encephalitis virus envelope proteins induced by an acidic pH.

The flavivirus envelope protein E undergoes irreversible conformational changes at a mildly acidic pH which are believed to be necessary for membrane fusion in endosomes. In this study we used a combination of chemical cross-linking and sedimentation analysis to show that the envelope proteins of th...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Allison, S L, Schalich, J, Stiasny, K, Mandl, C W, Kunz, C, Heinz, F X
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1995
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188630/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7529335/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.2.695-700.1995
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