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Epithelial cells immortalized by human papillomaviruses have premalignant characteristics in organotypic culture.

Three HPV-16--and four HPV-18--immortalized human foreskin keratinocyte cell lines were analyzed on organotypic epidermal raft cultures at various passage levels. This culture system allowed normal cultured keratinocytes to stratify and differentiate in a manner similar to normal epidermis. All seve...

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Main Authors: Blanton, R. A., Perez-Reyes, N., Merrick, D. T., McDougall, J. K.
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886282/
https://ncbi.nlm.nih.gov/pubmed/1848042
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