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Transgenic oncogene mice. Tumor phenotype predicts genotype.

The hypothesis that oncogenes influence tumor phenotype was tested by examining slides from 607 mammary tumors from 407 transgenic mice bearing the ras, myc, and/or neu oncogenes. Most tumors (91%) had patterns (phenotypes) that could not be classified by Dunn's standard nomenclature. The nonst...

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Autors principals: Cardiff, R. D., Sinn, E., Muller, W., Leder, P.
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886229/
https://ncbi.nlm.nih.gov/pubmed/1887859
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