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Hepatocyte-restricted constitutive activation of PPARα induces hepatoproliferation but not hepatocarcinogenesis

Peroxisome proliferator-activated receptor α (PPARα) is responsible for peroxisome proliferator-induced pleiotropic responses, including the development of hepatocellular carcinoma in rodents. However, it remains to be determined whether activation of PPARα only in hepatocytes is sufficient to induc...

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Detalhes bibliográficos
Main Authors: Yang, Qian, Ito, Shinji, Gonzalez, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885989/
https://ncbi.nlm.nih.gov/pubmed/17331954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgm046
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