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Keratinocyte serum-free medium maintains long-term liver gene expression and function in cultured rat hepatocytes by preventing the loss of liver-enriched transcription factors

Freshly isolated hepatocytes rapidly lose their differentiated properties when placed in culture. Therefore, production of a simple culture system for maintaining the phenotype of hepatocytes in culture would greatly facilitate their study. Our aim was to identify conditions that could maintain the...

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Detalhes bibliográficos
Main Authors: Li, Wan-Chun, Ralphs, Kate L., Slack, Jonathan M.W., Tosh, David
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885942/
https://ncbi.nlm.nih.gov/pubmed/17129745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2006.10.017
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