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Neuronal death enhanced by N-methyl-d-aspartate antagonists

Glutamate promotes neuronal survival during brain development and destroys neurons after injuries in the mature brain. Glutamate antagonists are in human clinical trials aiming to demonstrate limitation of neuronal injury after head trauma, which consists of both rapid and slowly progressing neurode...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Ikonomidou, Chrysanthy, Stefovska, Vanya, Turski, Lechoslaw
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18859/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11058158/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220412197
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