Reduced Heparan Sulfate Accumulation in Enterocytes Contributes to Protein-Losing Enteropathy in a Congenital Disorder of Glycosylation

Intestinal biopsy in a boy with gastroenteritis-induced protein-losing enteropathy (PLE) showed loss of heparan sulfate (HS) and syndecan-1 core protein from the basolateral surface of the enterocytes, which improved after PLE subsided. Isoelectric focusing analysis of serum transferrin indicated a...

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Hlavní autoři: Westphal, Vibeke, Murch, Simon, Kim, Soohyun, Srikrishna, Geetha, Winchester, Bryan, Day, Richard, Freeze, Hudson H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2000
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Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885788/
https://ncbi.nlm.nih.gov/pubmed/11106564
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