Co-Localization of Multiple Antigens and Specific DNA : A Novel Method Using Methyl Methacrylate-Embedded Semithin Serial Sections and Catalyzed Reporter Deposition

Co-localization of proteins and nucleic acid sequences by in situ hybridization and immunohistochemistry is frequently difficult as the process necessary to detect the target structure of one technique may negatively affect the target of the other. Morphological impairment may also limit the applica...

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Bibliographic Details
Main Authors: Mueller, Marcus, Wacker, Karin, Hickey, William F., Ringelstein, Erich B., Kiefer, Reinhard
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2000
Subjects:
Technical Advance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885787/
https://ncbi.nlm.nih.gov/pubmed/11106556
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