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Calpain Inhibitor I Reduces the Development of Acute and Chronic Inflammation

There is limited evidence that inhibition of the activity of the protease calpain I reduces inflammation. Here we investigate the effects of calpain inhibitor I in animal models of acute and chronic inflammation (carrageenan-induced pleurisy and collagen-induced arthritis). We report here for the fi...

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Detalhes bibliográficos
Main Authors: Cuzzocrea, Salvatore, McDonald, Michelle C., Mazzon, Emanuela, Siriwardena, Dilani, Serraino, Ivana, Dugo, Laura, Britti, Domenico, Mazzullo, Giuseppe, Caputi, Achille P., Thiemermann, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885785/
https://ncbi.nlm.nih.gov/pubmed/11106579
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