Synthetic multimeric peptides derived from the principal neutralization domain (V3 loop) of human immunodeficiency virus type 1 (HIV-1) gp120 bind to galactosylceramide and block HIV-1 infection in a human CD4-negative mucosal epithelial cell line.

The glycosphingolipid galactosylceramide (GalCer), which binds gp120 with high affinity and specificity, is a potential alternative receptor for human immunodeficiency virus type 1 (HIV-1) in some CD4-negative neural and epithelial human cells, including the human colonic epithelial cell line HT-29....

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Bibliografische Detailangaben
Veröffentlicht in:	J Virol
Hauptverfasser:	Yahi, N, Sabatier, J M, Baghdiguian, S, Gonzalez-Scarano, F, Fantini, J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188578/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7983725/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.1.320-325.1995
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Synthetic multimeric peptides derived from the principal neutralization domain (V3 loop) of human immunodeficiency virus type 1 (HIV-1) gp120 bind to galactosylceramide and block HIV-1 infection in a human CD4-negative mucosal epithelial cell line.

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