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Synthetic multimeric peptides derived from the principal neutralization domain (V3 loop) of human immunodeficiency virus type 1 (HIV-1) gp120 bind to galactosylceramide and block HIV-1 infection in a human CD4-negative mucosal epithelial cell line.

The glycosphingolipid galactosylceramide (GalCer), which binds gp120 with high affinity and specificity, is a potential alternative receptor for human immunodeficiency virus type 1 (HIV-1) in some CD4-negative neural and epithelial human cells, including the human colonic epithelial cell line HT-29....

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Bibliografiska uppgifter
Huvudupphovsmän: Yahi, N, Sabatier, J M, Baghdiguian, S, Gonzalez-Scarano, F, Fantini, J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC188578/
https://ncbi.nlm.nih.gov/pubmed/7983725
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