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Loss of Fas-Ligand Expression in Mouse Keratinocytes during UV Carcinogenesis

Skin cells containing excessive ultraviolet (UV) radiation-induced DNA damage are eliminated by apoptosis that involves the p53 pathway and Fas/Fas-Ligand (Fas-L) interactions. To determine whether dysregulation of apoptosis plays a role in skin cancer development through disruption of Fas/Fas-L int...

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Bibliographic Details
Main Authors: Ouhtit, Allal, Gorny, Alexander, Muller, H. Konrad, Hill, Laurie L., Owen-Schaub, Laurie, Ananthaswamy, Honnavara N.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885778/
https://ncbi.nlm.nih.gov/pubmed/11106570
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