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Hepatocyte Transplantation into Diseased Mouse Liver : Kinetics of Parenchymal Repopulation and Identification of the Proliferative Capacity of Tetraploid and Octaploid Hepatocytes

To examine the process of liver repopulation by transplanted hepatocytes, we developed transgenic mice carrying a mouse major urinary protein-urokinase-type plasminogen activator fusion transgene. Expression of this transgene induced diffuse hepatocellular damage beginning at 3 weeks of age, and hom...

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Autores principales: Weglarz, Teresa C., Degen, Jay L., Sandgren, Eric P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885759/
https://ncbi.nlm.nih.gov/pubmed/11106569
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