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Defective Interleukin-1 Receptor Antagonist Production Is Associated with Resistance of Acute Liver Graft Rejection to Steroid Therapy

Thirty percent of acute liver graft rejection episodes are resistant to steroids. As interleukin-1 (IL-1) is an important target of steroid therapy, we examined the possible involvement of reduced sensitivity of IL-1 production to steroids or defective production of its antagonist, IL-1Ra. Patients...

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Detalhes bibliográficos
Main Authors: Conti, Filomena, Breton, Sylvie, Batteux, Frédéric, Furlan, Valérie, Houssin, Didier, Weill, Bernard, Calmus, Yvon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885739/
https://ncbi.nlm.nih.gov/pubmed/11073827
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