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Coexpression of BMI-1 and EZH2 Polycomb Group Genes in Reed-Sternberg Cells of Hodgkin’s Disease

The human BMI-1 and EZH2 polycomb group (PcG) proteins are constituents of two distinct complexes of PcG proteins with gene regulatory activity. PcG proteins ensure correct embryonic development by suppressing homeobox genes, and they also contribute to regulation of lymphopoiesis. The two PcG compl...

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Detalhes bibliográficos
Main Authors: Raaphorst, Frank M., van Kemenade, Folkert J., Blokzijl, Tjasso, Fieret, Elly, Hamer, Karien M., Satijn, David P. E., Otte, Arie P., Meijer, Chris J. L. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885707/
https://ncbi.nlm.nih.gov/pubmed/10980109
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