High-Throughput Tissue Microarray Analysis of Cyclin E Gene Amplification and Overexpression in Urinary Bladder Cancer

Studies by comparative genomic hybridization revealed that the 19q13 chromosomal region is frequently amplified in bladder cancer. The cyclin E gene (CCNE), coding for a regulatory subunit of cyclin-dependent kinase 2, has been mapped to 19q13. To investigate the role of cyclin E alterations in blad...

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Autori principali: Richter, Jan, Wagner, Urs, Kononen, Juha, Fijan, André, Bruderer, James, Schmid, Ulrico, Ackermann, Daniel, Maurer, Robert, Alund, Göran, Knönagel, Hartmut, Rist, Marcus, Wilber, Kim, Anabitarte, Manuel, Hering, Franz, Hardmeier, Thomas, Schönenberger, Andreas, Flury, Renata, Jäger, Peter, Luc Fehr, Jean, Schraml, Peter, Moch, Holger, Mihatsch, Michael J., Gasser, Thomas, Kallioniemi, Olli P., Sauter, Guido
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885698/
https://ncbi.nlm.nih.gov/pubmed/10980118
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