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A recombineering based approach for high-throughput conditional knockout targeting vector construction

Functional analysis of mammalian genes in vivo is primarily achieved through analysing knockout mice. Now that the sequencing of several mammalian genomes has been completed, understanding functions of all the genes represents the next major challenge in the post-genome era. Generation of knockout m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chan, Waiin, Costantino, Nina, Li, Ruixue, Lee, Song Choon, Su, Qin, Melvin, David, Court, Donald L., Liu, Pentao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885671/
https://ncbi.nlm.nih.gov/pubmed/17426124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm163
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