Identification and characterization of monoclonal antibodies specific for polymorphic antigenic determinants within the V2 region of the human immunodeficiency virus type 1 envelope glycoprotein.

We have identified six monoclonal antibodies (MAbs) mapping to both linear and conformation-dependent epitopes within the V2 region of the human immunodeficiency virus type 1 clone HXB10. Three of the MAbs (12b, 66c, and 66a) were able to neutralize the molecular clones HXB10 and HXB2, with titers i...

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Dettagli Bibliografici

Pubblicato in:	J Virol
Autori principali:	Shotton, C, Arnold, C, Sattentau, Q, Sodroski, J, McKeating, J A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188567/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7527084/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.1.222-230.1995
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