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Idefix insulator activity can be modulated by nearby regulatory elements

Insulators play important roles in controlling gene activity and maintaining regulatory independence between neighbouring genes. In this article, we show that the enhancer-blocking activity of the insulator present within the LTR retrotransposon Idefix can be abolished if two copies of the region co...

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Hlavní autoři: Brasset, E., Bantignies, F., Court, F., Cheresiz, S., Conte, C., Vaury, C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885662/
https://ncbi.nlm.nih.gov/pubmed/17426135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm140
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