Substrate determinants for cleavage in cis and in trans by the hepatitis C virus NS3 proteinase.
Processing of the hepatitis C virus polyprotein is accomplished by a series of cotranslational and posttranslational cleavages mediated by host cell signalases and two virally encoded proteinases. Of these the NS3 proteinase is essential for processing at the NS3/4A, NS4A/4B, NS4B/5A, and NS5A/5B ju...
Gespeichert in:
| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1995
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188564/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7983710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.1.198-205.1995 |
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