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Substrate determinants for cleavage in cis and in trans by the hepatitis C virus NS3 proteinase.

Processing of the hepatitis C virus polyprotein is accomplished by a series of cotranslational and posttranslational cleavages mediated by host cell signalases and two virally encoded proteinases. Of these the NS3 proteinase is essential for processing at the NS3/4A, NS4A/4B, NS4B/5A, and NS5A/5B ju...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Bartenschlager, R, Ahlborn-Laake, L, Yasargil, K, Mous, J, Jacobsen, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1995
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188564/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7983710/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.1.198-205.1995
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