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A complex thiolate switch regulates the Bacillus subtilis organic peroxide sensor OhrR

Oxidation of protein thiolates is central to numerous redox-regulated processes. Bacillus subtilis OhrR is an organic peroxide sensor that represses expression of an inducible peroxiredoxin, OhrA. Here, we present evidence that oxidation of the sole cysteine residue in OhrR leads to a sulfenic acid-...

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Bibliographic Details
Main Authors: Lee, Jin-Won, Soonsanga, Sumarin, Helmann, John D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885573/
https://ncbi.nlm.nih.gov/pubmed/17502599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702081104
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