A human monoclonal antibody to a complex epitope in the V3 region of gp120 of human immunodeficiency virus type 1 has broad reactivity within and outside clade B.

We have used virus neutralization and antibody-binding techniques to define the epitope for a human monoclonal antibody, designated 19b, within the V3 region of the gp120 surface glycoprotein of human immunodeficiency virus type 1. Unusually, the 19b epitope encompasses residues on both flanks of th...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Moore, J P, Trkola, A, Korber, B, Boots, L J, Kessler, J A, McCutchan, F E, Mascola, J, Ho, D D, Robinson, J, Conley, A J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188555/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7527082/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.1.122-130.1995
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