Mutational analysis of the murine AIDS-defective viral genome reveals a high reversion rate in vivo and a requirement for an intact Pr60gag protein for efficient induction of disease.
Pr60gag appears to be the only protein encoded by the murine AIDS (MAIDS)-defective virus. To study the role of Pr60gag or some other sequences of the viral genome in the pathogenicity of the virus, we have generated mutants of the defective viral genome. These mutant defective viruses, prepared as...
Saved in:
| Published in: | J Virol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1995
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188548/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7983763/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.1.60-68.1995 |
| Tags: |
No Tags, Be the first to tag this record!
|