Syndecan-4–dependent Rac1 regulation determines directional migration in response to the extracellular matrix

Cell migration in wound healing and disease is critically dependent on integration with the extracellular matrix, but the receptors that couple matrix topography to migratory behavior remain obscure. Using nano-engineered fibronectin surfaces and cell-derived matrices, we identify syndecan-4 as a ke...

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Bibliografische gegevens
Hoofdauteurs: Bass, Mark D., Roach, Kirsty A., Morgan, Mark R., Mostafavi-Pour, Zohreh, Schoen, Tobias, Muramatsu, Takashi, Mayer, Ulrike, Ballestrem, Christoph, Spatz, Joachim P., Humphries, Martin J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2007
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885470/
https://ncbi.nlm.nih.gov/pubmed/17485492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200610076
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