Syndecan-4–dependent Rac1 regulation determines directional migration in response to the extracellular matrix

Cell migration in wound healing and disease is critically dependent on integration with the extracellular matrix, but the receptors that couple matrix topography to migratory behavior remain obscure. Using nano-engineered fibronectin surfaces and cell-derived matrices, we identify syndecan-4 as a ke...

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Bibliografiske detaljer
Main Authors: Bass, Mark D., Roach, Kirsty A., Morgan, Mark R., Mostafavi-Pour, Zohreh, Schoen, Tobias, Muramatsu, Takashi, Mayer, Ulrike, Ballestrem, Christoph, Spatz, Joachim P., Humphries, Martin J.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2007
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885470/
https://ncbi.nlm.nih.gov/pubmed/17485492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200610076
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