Syndecan-4–dependent Rac1 regulation determines directional migration in response to the extracellular matrix

Cell migration in wound healing and disease is critically dependent on integration with the extracellular matrix, but the receptors that couple matrix topography to migratory behavior remain obscure. Using nano-engineered fibronectin surfaces and cell-derived matrices, we identify syndecan-4 as a ke...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bass, Mark D., Roach, Kirsty A., Morgan, Mark R., Mostafavi-Pour, Zohreh, Schoen, Tobias, Muramatsu, Takashi, Mayer, Ulrike, Ballestrem, Christoph, Spatz, Joachim P., Humphries, Martin J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2007
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885470/
https://ncbi.nlm.nih.gov/pubmed/17485492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200610076
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