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The Efficacy a DNA Vaccine Containing Inserted and Replicated Regions of the E7 Gene for Treatment of HPV 16 Induced Tumors
A majority of cervical cancers are associated with HPV-16. A DNA vaccine (E7IR) was designed for prophylactic and therapeutic treatment of HPV-16+ tumors containing two repeats of the E7 gene to inactivate transformation and duplicate available epitopes. Mice were vaccinated then tumor challenged, o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885421/ https://ncbi.nlm.nih.gov/pubmed/17241713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2006.12.045 |
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