A switch region determines the cell type-specific positive or negative action of YY1 on the activity of the human papillomavirus type 18 promoter.

YY1 is a zinc finger transcription factor which acts as either a repressor or an activator dependent on the promoter context. YY1 is a potent activator of the genuine human papillomavirus type 18 (HPV-18) upstream regulatory region (URR) in HeLa cells, which are known for high-level expression of th...

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Bibliografske podrobnosti
Main Authors: Bauknecht, T, Jundt, F, Herr, I, Oehler, T, Delius, H, Shi, Y, Angel, P, Zur Hausen, H
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC188542/
https://ncbi.nlm.nih.gov/pubmed/7983700
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