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Whole-Genome Cartography of Estrogen Receptor α Binding Sites

Using a chromatin immunoprecipitation-paired end diTag cloning and sequencing strategy, we mapped estrogen receptor α (ERα) binding sites in MCF-7 breast cancer cells. We identified 1,234 high confidence binding clusters of which 94% are projected to be bona fide ERα binding regions. Only 5% of the...

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Detalhes bibliográficos
Main Authors: Lin, Chin-Yo, Vega, Vinsensius B, Thomsen, Jane S, Zhang, Tao, Kong, Say Li, Xie, Min, Chiu, Kuo Ping, Lipovich, Leonard, Barnett, Daniel H, Stossi, Fabio, Yeo, Ailing, George, Joshy, Kuznetsov, Vladimir A, Lee, Yew Kok, Charn, Tze Howe, Palanisamy, Nallasivam, Miller, Lance D, Cheung, Edwin, Katzenellenbogen, Benita S, Ruan, Yijun, Bourque, Guillaume, Wei, Chia-Lin, Liu, Edison T
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885282/
https://ncbi.nlm.nih.gov/pubmed/17542648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030087
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