Escape of HIV-1 from a Small Molecule CCR5 Inhibitor Is Not Associated with a Fitness Loss

Fitness is a parameter used to quantify how well an organism adapts to its environment; in the present study, fitness is a measure of how well strains of human immunodeficiency virus type 1 (HIV-1) replicate in tissue culture. When HIV-1 develops resistance in vitro or in vivo to antiretroviral drug...

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Bibliographic Details
Main Authors: Anastassopoulou, Cleo G, Marozsan, Andre J, Matet, Alexandre, Snyder, Amy D, Arts, Eric J, Kuhmann, Shawn E, Moore, John P
Format: Artigo
Language:Inglês
Published: Public Library of Science 2007
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885273/
https://ncbi.nlm.nih.gov/pubmed/17542646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030079
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