Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (Retinaldehyde dehydrogenase 1)

One of the metabolic fates of 3-deoxyglucosone, a product of protein deglycation and a potent glycating agent, is to be oxidized to 2-keto-3-deoxygluconate, but the enzyme that catalyses this reaction is presently unknown. Starting from human erythrocytes, which are known to convert 3-deoxyglucosone...

Full description

Saved in:
Bibliographic Details
Main Authors: Collard, François, Vertommen, Didier, Fortpied, Juliette, Duester, Gregg, Van Schaftingen, Emile
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885224/
https://ncbi.nlm.nih.gov/pubmed/17175089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2006.11.005
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items