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Effects of the direct thrombin inhibitor dabigatran on ex vivo coagulation time in orthopaedic surgery patients: a population model analysis

AIMS: To describe the pharmacokinetic–pharmacodynamic (PK–PD) characteristics of the direct thrombin inhibitor dabigatran in hip replacement patients by assessing coagulation parameters activated partial thromboplastin time (aPTT) and ecarin clotting time (ECT), interindividual variability and facto...

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書誌詳細
主要な著者: Liesenfeld, Karl-Heinz, Schäfer, Hans G, Trocóniz, Iñaki F, Tillmann, Christiane, Eriksson, Bengt I, Stangier, Joachim
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Science Inc 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885168/
https://ncbi.nlm.nih.gov/pubmed/17061960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02667.x
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