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HapMap, pharmacogenomics, and the goal of personalized prescribing
Most of the gene variants that have been identified in the last 50 years have affected individual drug responses through effects on pharmacokinetics. Gene variants that affect a drug’s pharmacodynamics, such as polymorphisms in receptors or signalling molecules, have been more difficult to identify....
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| Natura: | Artigo |
| Lingua: | Inglês |
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Blackwell Science Inc
2006
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885109/ https://ncbi.nlm.nih.gov/pubmed/16722846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02683.x |
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