Effects of lasofoxifene on the pharmacokinetics and pharmacodynamics of single-dose warfarin

AIM: To investigate the effect of steady-state lasofoxifene on the pharmacokinetics and pharmacodynamics of warfarin. METHODS: Twelve healthy postmenopausal women received warfarin (single 20-mg dose) alone and during lasofoxifene. R- and S-warfarin concentrations, prothrombin time (PT) and internat...

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Main Authors: Ouellet, Daniele, Bramson, Candace, Carvajal-Gonzalez, Santos, Roman, Doina, Randinitis, Edward, Remmers, Ann, Gardner, Mark J
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2006
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885106/
https://ncbi.nlm.nih.gov/pubmed/16722839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02589.x
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