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Selectivity of NSAIDs for COX-2 and cardiovascular outcome

BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) with increased selectivity for the cyclooxygenase-2 (COX-2) isoform reduce gastrotoxicity but may increase adverse cardiovascular events. METHODS: We searched the literature for studies that reported the odds ratio (OR) for such events follow...

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Autors principals: Maxwell, S R J, Payne, R A, Murray, G D, Webb, D J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885096/
https://ncbi.nlm.nih.gov/pubmed/16842401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02620.x
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