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Trimethoprim–sulphamethoxazole does not affect the pharmacokinetics of sirolimus in renal transplant recipients

AIMS: The influence of the trimethoprim–sulphamethoxazole combination on the steady-state pharmacokinetics of sirolimus, a potent macrocyclic immunosuppressant, was studied in renal transplant recipients. METHODS: Fifteen kidney transplant recipients were treated with sirolimus 8–23 mg m(−2) in comb...

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Main Authors: Böttiger, Ylva, Brattström, Christina, Bäckman, Lars, Claesson, Kerstin, Burke, James T
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884939/
https://ncbi.nlm.nih.gov/pubmed/16236048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02475.x
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