Polymorphisms in genes encoding acetylsalicylic acid metabolizing enzymes are unrelated to upper gastrointestinal health in cardiovascular patients on acetylsalicylic acid

BACKGROUND: As acetylsalicylic acid is metabolized by UDP-glucuronosyltransferase 1A6 (UGT1A6) and cytochrome P450 2C9 (CYP2C9), interindividual differences in activity of these enzymes may modulate the effects and side-effects of acetylsalicylic acid. The objective of this study was to assess wheth...

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Bibliografiske detaljer
Main Authors: van Oijen, Martijn G H, Huybers, Sylvie, Peters, Wilbert H M, Drenth, Joost P H, Laheij, Robert J F, Verheugt, Freek W A, Jansen, Jan B M J
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2005
Fag:
Pharmacogenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884887/
https://ncbi.nlm.nih.gov/pubmed/16305586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02495.x
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