Population pharmacokinetic analysis for nelfinavir and its metabolite M8 in virologically controlled HIV-infected patients on HAART

AIMS: To describe the pharmacokinetics of nelfinavir and its main metabolite M8 in HIV-infected patients with a sustained virological response, to characterize the effect of covariates and to estimate inter- and intra-individual variability in the pharmacokinetics. METHODS: Three hundred and twenty...

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Autori principali: Panhard, X, Goujard, C, Legrand, M, Taburet, A M, Diquet, B, Mentré, F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2005
Soggetti:
Pharmacokinetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884828/
https://ncbi.nlm.nih.gov/pubmed/16187971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02456.x
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