Utilization of pulse oximetry for the study of the inhibitory effects of antiviral agents on influenza virus in mice.

Pulmonary disease in mice induced by influenza virus was monitored by measurement of oxygen saturation (SaO2) in blood with a pulse oximeter. The SaO2 declined in inverse proportion to the viral inoculum. The known antiviral agent ribavirin inhibited the SaO2 decline, prevented death, lowered lung c...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Sidwell, R W, Huffman, J H, Gilbert, J, Moscon, B, Pedersen, G, Burger, R, Warren, R P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188461/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1605614/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.2.473
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