Effect of duloxetine on tolterodine pharmacokinetics in healthy volunteers

AIM: To investigate the effect of duloxetine on the pharmacokinetics and tolerability of tolterodine and its active 5-hydroxymethyl metabolite (5-HM). METHODS: Sixteen healthy subjects received two 5-day treatment regimens in a randomized, double-blinded, crossover fashion: tolterodine (2 mg, BID) +...

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Bibliographic Details
Main Authors: Hua, Teng C, Pan, Alan, Chan, Clark, Poo, Yeo K, Skinner, Michael H, Knadler, Mary P, Gonzales, Celedon R, Wise, Stephen D
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2004
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Short Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884503/
https://ncbi.nlm.nih.gov/pubmed/15089819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02068.x
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