An investigation of components of variance and tachyphylaxis in a placebo-controlled intravenous tyramine study

AIMS: To explore inter- and intra-volunteer variability for the dose of intravenous tyramine eliciting a 20 mmHg increase in systolic blood pressure from baseline (TYR20) and to evaluate potential tachyphylaxis. METHODS: Twelve healthy volunteers received blinded placebo-controlled ascending and des...

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Main Authors: Cantarini, M V, Watkins, C L, Growcott, J, Hughes, A M
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2004
Fag:
Short Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884499/
https://ncbi.nlm.nih.gov/pubmed/15089820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02069.x
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