Safety and pharmacokinetics of multiple doses of intravenous ofloxacin in healthy volunteers.

The safety and pharmacokinetics of ofloxacin in 48 healthy male volunteers were studied in a two-center, randomized, double-blind, placebo-controlled study. Ofloxacin (200 or 400 mg) or placebo was administered as 1-h infusions every 12 h for 7 days. Plasma ofloxacin concentrations were measured by...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Guay, D R, Opsahl, J A, McMahon, F G, Vargas, R, Matzke, G R, Flor, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188432/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1605596/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.2.308
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