Relationship of pharmacokinetics and drug distribution in tissue to increased safety of amphotericin B colloidal dispersion in dogs.

The safety, pharmacokinetics, and distribution in tissue of an amphotericin B (AmB)-cholesteryl sulfate colloidal dispersion (ABCD) were compared with those of micellar amphotericin B-deoxycholate (m-AmB). Dogs received 14 daily injections of ABCD (0.6 to 10 mg/kg of body weight per day) or m-AmB (0...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Fielding, R M, Singer, A W, Wang, L H, Babbar, S, Guo, L S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188430/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1605595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.2.299
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