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Effects of sex on the pharmacokinetic and pharmacodynamic properties of quinidine

AIMS: To investigate the source of the apparent increased susceptibility of women to develop QT interval prolongation and torsade de pointes after the administration of drugs that delay cardiac repolarization. METHODS: Plasma quinidine concentrations and electrocardiographic changes (QRS and QT inte...

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Detalhes bibliográficos
Main Authors: El-Eraky, Hala, Thomas, Simon H L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884276/
https://ncbi.nlm.nih.gov/pubmed/12895193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01865.x
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