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Pharmacokinetics of morphine are not altered in subjects with Gilbert's syndrome
AIMS: To verify that Gilbert's syndrome, which is caused by decreased glucuronidation capacity of the UDP-glucuronosyl transferase (UGT)1A1, does not account for impaired morphine clearance. METHODS: Noncompartmental pharmacokinetic parameters for morphine and its glucuronide metabolites were c...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1884272/ https://ncbi.nlm.nih.gov/pubmed/12895198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01866.x |
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